Improving Pediatric Sepsis Outcomes

Challenge sepsis.
Change lives.

Every year, more than 3 million children worldwide die from sepsis, including 7,000 in the U.S. Nearly half who survive return to the hospital at least once and more than a third experience some disability.

From 2016-2023, 66 children’s hospitals across the U.S. came together to share data and collaborate on solutions to reduce deaths and complications due to sepsis. Eight years of learning and data from more than 100,000 sepsis cases culminated in a comprehensive resource for improving pediatric sepsis care.

Called a change package, this improvement toolkit equips hospitals with practical resources and evidence-based strategies proven to reduce pediatric deaths from sepsis.

What's in the change package?

A lifesaving bundle of care

Strategies for effective implementation

Key measures for tracking performance

70+ sepsis tools from high-performing hospitals

Improving Pediatric Sepsis Outcomes Collaborative

The Improving Pediatric Sepsis Outcomes (IPSO) collaborative was a multi-year, multi-site, and multi-disciplinary effort to decrease sepsis-associated mortality.

Using multimodal quality improvement (QI) methodologies, evidence-based care bundles, and data-driven performance evaluation, the collaborative decreased not only mortality rates but also hospital days and antibiotic use among children with sepsis.

calendar
hospital
magnifying-glass
heart

8

years

66

hospitals convened

100K+

cases analyzed

570+

estimated lives saved

Improving Pediatric Sepsis Outcomes

Challenge sepsis.
Change lives.

Every year, more than 3 million children worldwide die from sepsis, including 7,000 in the U.S. Nearly half who survive return to the hospital at least once and more than a third experience some disability.

From 2016-2023, 66 children’s hospitals across the U.S. came together to share data and collaborate on solutions to reduce deaths and complications due to sepsis. Eight years of learning and data from more than 100,000 sepsis cases culminated in a comprehensive resource for improving pediatric sepsis care.

Called a change package, this improvement toolkit equips hospitals with practical resources and evidence-based strategies proven to reduce pediatric deaths from sepsis.

What's in the change package?

A lifesaving bundle of care

Strategies for effective implementation

Key measures for tracking performance

70+ sepsis tools from high-performing hospitals

Improving Pediatric Sepsis Outcomes Collaborative

The Improving Pediatric Sepsis Outcomes (IPSO) collaborative was a multi-year, multi-site, and multi-disciplinary effort to decrease sepsis-associated mortality.

Using multimodal quality improvement (QI) methodologies, evidence-based care bundles, and data-driven performance evaluation, the collaborative decreased not only mortality rates but also hospital days and antibiotic use among children with sepsis.

calendar
hospital
magnifying-glass
heart

8

years

66

hospitals convened

100K+

cases analyzed

570+

estimated lives saved

Improving Pediatric Sepsis Outcomes

Challenge sepsis.
Change lives.

Every year, more than 3 million children worldwide die from sepsis, including 7,000 in the U.S. Nearly half who survive return to the hospital at least once and more than a third experience some disability.

From 2016-2023, 66 children’s hospitals across the U.S. came together to share data and collaborate on solutions to reduce deaths and complications due to sepsis. Eight years of learning and data from more than 100,000 sepsis cases culminated in a comprehensive resource for improving pediatric sepsis care.

Called a change package, this improvement toolkit equips hospitals with practical resources and evidence-based strategies proven to reduce pediatric deaths from sepsis.

What's in the change package?

A lifesaving bundle of care

Strategies for effective implementation

Key measures for tracking performance

70+ sepsis tools from high-performing hospitals

Improving Pediatric Sepsis Outcomes Collaborative

The Improving Pediatric Sepsis Outcomes (IPSO) collaborative was a multi-year, multi-site, and multi-disciplinary effort to decrease sepsis-associated mortality.

Using multimodal quality improvement (QI) methodologies, evidence-based care bundles, and data-driven performance evaluation, the collaborative decreased not only mortality rates but also hospital days and antibiotic use among children with sepsis.

calendar

8

years

hospital

66

hospitals convened

magnifying-glass

100K+

cases analyzed

heart

570+

estimated lives saved