Every year, more than 3 million children worldwide die from sepsis, including 7,000 in the U.S. Nearly half who survive return to the hospital at least once and more than a third experience some disability.
From 2016-2023, 66 children’s hospitals across the U.S. came together to share data and collaborate on solutions to reduce deaths and complications due to sepsis. Eight years of learning and data from more than 100,000 sepsis cases culminated in a comprehensive resource for improving pediatric sepsis care.
Called a change package, this improvement toolkit equips hospitals with practical resources and evidence-based strategies proven to reduce pediatric deaths from sepsis.
The Improving Pediatric Sepsis Outcomes (IPSO) collaborative was a multi-year, multi-site, and multi-disciplinary effort to decrease sepsis-associated mortality.
Using multimodal quality improvement (QI) methodologies, evidence-based care bundles, and data-driven performance evaluation, the collaborative decreased not only mortality rates but also hospital days and antibiotic use among children with sepsis.
8
years
66
hospitals convened
100K+
cases analyzed
570+
estimated lives saved
Improving Pediatric Sepsis Outcomes
Challenge sepsis. Change lives.
Every year, more than 3 million children worldwide die from sepsis, including 7,000 in the U.S. Nearly half who survive return to the hospital at least once and more than a third experience some disability.
From 2016-2023, 66 children’s hospitals across the U.S. came together to share data and collaborate on solutions to reduce deaths and complications due to sepsis. Eight years of learning and data from more than 100,000 sepsis cases culminated in a comprehensive resource for improving pediatric sepsis care.
Called a change package, this improvement toolkit equips hospitals with practical resources and evidence-based strategies proven to reduce pediatric deaths from sepsis.
The Improving Pediatric Sepsis Outcomes (IPSO) collaborative was a multi-year, multi-site, and multi-disciplinary effort to decrease sepsis-associated mortality.
Using multimodal quality improvement (QI) methodologies, evidence-based care bundles, and data-driven performance evaluation, the collaborative decreased not only mortality rates but also hospital days and antibiotic use among children with sepsis.
8
years
66
hospitals convened
100K+
cases analyzed
570+
estimated lives saved
Improving Pediatric Sepsis Outcomes
Challenge sepsis. Change lives.
Every year, more than 3 million children worldwide die from sepsis, including 7,000 in the U.S. Nearly half who survive return to the hospital at least once and more than a third experience some disability.
From 2016-2023, 66 children’s hospitals across the U.S. came together to share data and collaborate on solutions to reduce deaths and complications due to sepsis. Eight years of learning and data from more than 100,000 sepsis cases culminated in a comprehensive resource for improving pediatric sepsis care.
Called a change package, this improvement toolkit equips hospitals with practical resources and evidence-based strategies proven to reduce pediatric deaths from sepsis.
The Improving Pediatric Sepsis Outcomes (IPSO) collaborative was a multi-year, multi-site, and multi-disciplinary effort to decrease sepsis-associated mortality.
Using multimodal quality improvement (QI) methodologies, evidence-based care bundles, and data-driven performance evaluation, the collaborative decreased not only mortality rates but also hospital days and antibiotic use among children with sepsis.